Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus in mice
نویسندگان
چکیده
منابع مشابه
Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus in mice.
The ability to selectively inactivate immune cells with immunosuppressants is a much sought-after modality for the treatment of systemic lupus erythematosus and autoimmunity in general. Here, we designed and tested a novel nanogel drug delivery vehicle for the immunosuppressant mycophenolic acid (MPA). Treatment with MPA-loaded nanogels increased the median survival time (MST) of lupus-prone NZ...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2013
ISSN: 0021-9738
DOI: 10.1172/jci65907